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Adal Mirza

Professor, University of Southampton, UK

Title: A comparison between HPV positive and negative cervical disease in Head and Neck Squamous Cell Carcinoma

Biography

Biography: Adal Mirza

Abstract

Lymph node metastasis in Head and Neck Squamous Cell Carcinoma (HNSCC) is common at the time of presentation. Prior to the advent of Human Papilloma Virus (HPV)-driven disease, regional metastasis was associated with poor prognosis, but today advanced HPV(+) disease as per the Tumor Nodes Metastasis (TNM) classification, demonstrates a different natural history with improved responses to treatment and 5-year survival. This is a retrospective review of patients undergoing neck dissection for HNSCC and demonstrates remarkable discrepancies in outcomes between HPV(+) and HPV(-) disease.